Understanding the Disease Burden and Antibiotic Resistance in Patients With Bloodstream Infections Caused by Enterobacteriaceae in Australia

Optimising genomic approaches for identifying vancomycin-resistant Enterococcus faecium transmission in healthcare settings

C Higgs, NL Sherry, T Seemann, K Horan, H Walpola, P Kinsella, K Bond, DA Williamson, C Marshall, JC Kwong, ML Grayson, TP Stinear, CL Gorrie, BP Howden

2022-12-01

Vancomycin-resistant Enterococcus faecium (VREfm) is a major nosocomial pathogen. Identifying VREfm transmission dynamics permits ..

State-wide genomic epidemiology investigations of COVID-19 in healthcare workers in 2020 Victoria, Australia: Qualitative thematic analysis to provide insights for future pandemic preparedness

AE Watt, NL Sherry, P Andersson, CR Lane, S Johnson, M Wilmot, K Horan, M Sait, SA Ballard, C Crachi, DJ Beck, C Marshall, MA Kainer, R Stuart, C McGrath, JC Kwong, P Bass, PG Kelley, A Crowe, S Guy

2022-08-01

Background: COVID-19 has affected many healthcare workers (HCWs) globally. We performed state-wide SARS-CoV-2 genomic epidemiologi..

Key parameters for genomics-based real-time detection and tracking of multidrug-resistant bacteria: a systematic analysis

CL Gorrie, AG Da Silva, DJ Ingle, C Higgs, T Seemann, TP Stinear, DA Williamson, JC Kwong, ML Grayson, NL Sherry, BP Howden

2021-11-01

Background: Pairwise single nucleotide polymorphisms (SNPs) are a cornerstone of genomic approaches to the inference of transmissi..

Genomics for molecular epidemiology and detecting transmission of carbapenemase-producing enterobacterales in Victoria, Australia, 2012 to 2016

NL Sherry, CR Lane, JC Kwong, M Schultz, M Sait, K Stevens, S Ballard, AG Da Silva, T Seemann, CL Gorrie, TP Stinear, DA Williamson, J Brett, A Van Diemen, M Easton, BP Howden

2019-01-01

Carbapenemase-producing Enterobacterales (CPE) are being increasingly reported in Australia, and integrated clinical and genomic s..

Emerging Gram negative resistance to last-line antimicrobial agents fosfomycin, colistin and ceftazidime-avibactam–epidemiology, laboratory detection and treatment implications

N Sherry, B Howden

2018-04-03

Introduction: Multidrug-resistant (MDR) and extensively-drug-resistant (XDR) Gram-negative bacteria have emerged as a major threat..

Translating genomics into practice for real-time surveillance and response to carbapenemase-producing Enterobacteriaceae: Evidence from a complex multi-institutional KPC outbreak

JC Kwong, CR Lane, F Romanes, AG da Silva, M Easton, K Cronin, MJ Waters, T Tomita, K Stevens, MB Schultz, SL Baines, NL Sherry, GP Carter, A Mu, M Sait, SA Ballard, T Seemann, TP Stinear, BP Howden

2018-01-01

Background: Until recently, Klebsiella pneumoniae carbapenemase (KPC)- producing Enterobacteriaceae were rarely identified in Aust..